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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Described below are the key drug-food interactions associated with Cialis topically.id
  • References:
  • Protease inhibitors ( overwheline f ) is an anti-cancer medication that reduces blood pressure by increasing blood flow to the penis.Ex. riluzole ( used in managing fungal infections) is an anti-fungal medication that reduces blood pressure by blocking the growth of fungus.

    Interactions

    A. Top Drug-Drug Interactions:

    1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

    2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

    3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

    Other Drug-Drug interactions:

    • Ketoconazole, itraconazole (used to manage fungal infection)
    • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
    • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
    • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
    • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

    B. Drug-Food Interactions:

    Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

    1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
    2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
    3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
    4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
    All drug-food interactions can cause mild side effects or alter the medication's effectiveness. However, not all possible interactions. For example, may increase or decrease in blood pressure, could enhance hypotension, or could increase or decrease the effectiveness of the medication.

    If you take Cialis with medications such as alpha-blockers or other medications for blood pressure, this may interact with it. This can increase the risk of side effects or alter the medication's effectiveness. If you miss a dose, take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take a double dose to make up for a missed one.

    C.

    If Cialis is taken with alpha-blockers such as prazosin, tamsulosin, or alfuzosin, or with other medications for blood pressure, or with Cialis with other antibiotics, these medications may interact with these medications. This may cause symptoms of dizziness or fainting, or affect the effectiveness of the medication.

    Cialis (Tadalafil) is a medication that is used to treat male sexual function problems (impotence or erectile dysfunction-ED). Erectile dysfunction problems can be caused by a number of conditions, including diabetes, high blood pressure, high cholesterol, and certain conditions in which sexual stimulation may be necessary. Cialis works by increasing blood flow to the penis, which can help men achieve and maintain an erection. Cialis is available in three different strengths: 5mg, 10mg, and 20mg. Men who have taken Cialis must take at least one dose before sexual activity.

    There are two types of Cialis: phosphodiesterase type 5 (PDE5) inhibitors and non-phosphodiesterase type 5 (NPDE5) inhibitors. Cialis is available only with a prescription. Men who are taking nitrates for chest pain or heart problems should avoid Cialis, as it can lead to a dangerous drop in blood pressure. Cialis does not work against chest pain or heart problems.

    There are two types of NPDE5 inhibitors: PDE5 inhibitors and non-phosphodiesterase type 5 (NPDE5). PDE5 inhibitors treat erectile dysfunction by blocking an enzyme called phosphodiesterase type 5. NPDE5 inhibitors treat pulmonary arterial hypertension by blocking an enzyme called phosphodiesterase type 5. PDE5 inhibitors work by inhibiting an enzyme called phosphodiesterase type 5 that breaks down cyclic guanosine monophosphate (cGMP), causing the smooth muscles in blood vessels to relax. By inhibiting PDE5, NPDE5 reduces the levels of cGMP in the blood and allows blood to flow into the penis.

    Men who are taking nitrates for high blood pressure or who have experienced chest pain after taking Cialis can experience a drop in blood pressure.

    Nitrates work by relaxing blood vessels. They do not cause a drop in blood pressure. Cialis can increase the blood flow to the penis, which can help men achieve and maintain an erection. Men who have experienced chest pain after taking Cialis should avoid nitrates.

    Buy Cialis (Tadalafil) for the Treatment of Erectile Dysfunction

    We specialize in providing our over 1,000,000 customers with relevant product and condition information created by our professional editorial staff which includes our team of medical writers, medical practitioners, and health educators.

    What is tadalafil (generic Cialis)?

    Tadalafil (generic Cialis) is the generic name for Cialis. Tadalafil is used to treat erectile dysfunction (impotence or erectile dysfunction-ED). ED can happen only when sexual stimulation occurs. Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor. It works by increasing blood flow to the penis. This helps men achieve and maintain an erection. Men who take tadalafil for erectile dysfunction should avoid sexual activity because of the risk of side effects.

    Tadalafil is available in three different strengths: 5mg, 10mg, and 20mg. Men who have taken 5mg or 10mg tadalafil must take at least one dose before sexual activity. Men who are taking tadalafil for erectile dysfunction can experience a drop in blood pressure. Men who take tadalafil for erectile dysfunction can experience a drop in blood pressure. This is because tadalafil has a lower concentration of tadalafil in the blood. Tadalafil does not work against heart problems. Men who have experienced chest pain after taking tadalafil must avoid sexual activity because of the risk of side effects.

    Tadalafil does not work against prostate problems. It does not treat enlarged prostate gland (benign prostatic hyperplasia or BPH). Tadalafil does not work against male breast cancer. Tadalafil does not treat pulmonary arterial hypertension.

    Tadalafil is available only with a prescription.

    Highlights

    • Cialis and generic tadalafil are trusted and effective treatments for erectile dysfunction (ED).
    • Cialis and viagra are both effective ED treatments available in the United States.
    • dual dose of generic tadalafil for better blood flow to the penis.
    • Same-strength of cialis and generic tadalafil are equally effective.
    • Viagra dose is slightly different: slightly longer action, longer duration of action.
    • Viagra and cialis work similarly to get the best results.
    • Both medications can be obtained without a prescription in the United States.

    is a sensitive and specific medication that provides men with the boost they need to get and stay intimate with theWB. It contains the active ingredient tadalafil, which belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by increasing blood flow to the penis, which helps men get and sustain an erection when sexually stimulated.

    How to use tadalafil

    Before you start taking tadalafil, carefully review the instructions provided to you by your doctor. Follow all directions included with the product package. Do not use more of this medication, or more often, than prescribed.

    Your doctor may recommend a lower dose if tadalafil does not work as well as previous ones. Common side effects of tadalafil may include headaches, nasal congestion, and indigestion. Contact your doctor if you experience these:

    • Back pain (muscle or joint pain)
    • Back pain or muscle aches (muscle spasms)
    • Breast pain (prostate pain)
    • Breathing and talking difficulties
    • Cloudier skin, peeling sun, or other side effects of tadalafil
    • Chest pain (such as chest pain due to irregular heartbeat)
    • Dizziness or fainting

    Contact your doctor or get medical help right away if you experience severe or persistent side effects.

    If you need medical help right now, or your symptoms improve, you can contact Cancer Research Center of the Health Sciences on +1-800-CART.

    What is tadalafil?

    Tadalafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. These medications work by increasing blood flow to the penis, which helps you get and stay erect.

    How does tadalafil work for ED?

    What are the possible side effects of tadalafil?

    Most side effects of tadalafil are mild or moderate, but it may affect some people differently.

    Common side effects of tadalafil may include headaches, nasal congestion, indigestion, dizziness, or heart problems. Contact your doctor or get medical help right away if you notice any of these side effects:

    • Chest pain or irregular heartbeat
    • Erection problems (such as erectile dysfunction, Peyronie's disease, or serious heart problems)
    • Headache or dizziness
    • Feeling sleepy or tired
    • Skin sensitivity to light or heat
    • Stuffy or runny nose

    Contact your doctor or get medical help right away if you experience serious side effects, including:

    • Sudden vision loss
    • Chest pain or angina (muscle problems)
    • Sudden hearing loss
    • Severe allergic reactions (rash, swelling, or difficulty breathing)
    • Chest pain that doesn't go away
    • Chest pain with irregular heartbeat
    • Seizures

    Rare but serious side effects of tadalafil may include sudden vision loss, hearing loss, or serious skin reactions such as blistering, peeling, or discoloration of skin.

    To avoid unwanted side effects, you can take tadalafil with or without food.